Everything you need to know on magnesium glycinate

Everything you need to know on magnesium glycinate

Magnesium glycinate

Magnesium glycinate (or bisglycinate) is a highly bioavailable form of magnesium made by chelating magnesium to the amino acid glycine. Chelated magnesium is a unique preparation method that offers increased stability, better bioavailability, and less chance of impacting the digestive tract. 

Magnesium glycinate is thought to be one of the most relaxing forms of magnesium, partly because of what it is chelated to, in this case glycine. Glycine (also known as 2-Aminoacetic Acid) is an amino acid and a neurotransmitter. It has a broad range of roles in the body, from regulating blood sugar to faciliating the production DNA and RNA. It is also one of three amino acids that your body uses to make glutathione, a powerful antioxidant that helps protect your cells against oxidative damage caused by free radicals.

Although glycine can be both excitatory and inhibitory, many people find it relaxing on the nervous system. Studies show that higher levels of this amino acid may, help you fall asleep more quickly, reduce symptoms of insomnia and promote deeper more restful sleep.

Why add B6?

B6 is one of the eight B vitamins that in its active form, is known as coenzyme pyridoxal-5-phosphate (PLP or P5P). Unlike the cheap form of B6 known as Pyridoxine Hydrochloride (inactive) which is poorly assimilated, active P5P is involved in more than 140 different metabolic reactions in your cells, including facilitating uptake of magnesium.

It exerts modulatory effects on key neurotransmitters that affect depression and anxiety, and may act peripherally to reduce the physiological impact of corticosteroid release. It plays a key role in gluconeogenesis and glycogenolysis, metabolism of nutrients & histamines, synthesis of hemoglobin and gene expression.

Research suggests that that the combination of magnesium and vitamin B6 is more effective in reducing stress compared with magnesium alone in stressed individuals. 

It's important to note that B vitamins work together and in balance. We use a small dose of B6 in our magnesium glycinate to mirror what we find food and to not upset this balance.

Which magnesium to use

We recommend people try different forms of magnesium to see which form they prefer. Some of our customers like to take magnesium malate in the morning and magnesium glycinate in the evening. It's important to listen to your body and find the form and dose that works for you.


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